Project title:

Identification and development of inhibitors of the Zika virus NS2B/3 protease

Chief Investigator:

Dr Nicholas Eyre

Funding Amount:



The University of Adelaide


The recent outbreak of Zika virus (ZIKV) in South America and its association with birth defects has been declared by the World Health Organization (WHO) as a “public health emergency of international concern”. Accordingly, there is an urgent need for improved diagnostics, vaccines and antiviral therapies to combat the spread and impact of ZIKV. This project will identify inhibitors of the ZIKV NS2B/3 protease that may be developed as future antiviral therapies to treat ZIKV infection.

Review Research Outcomes

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