Role of parental age on offspring health.
Associate Professor Rebecca Robker
University of Adelaide
Evidence linking advanced age of both mothers and fathers to autism spectrum disorders in children is becoming impossible to ignore. This project will elucidate the defects that occur in eggs and sperm with aging and test whether reversing them with a novel therapeutic can mitigate anxiety-like behaviours in offspring. This research is essential as more couples choose to have children later in life. The outcomes will improve our understanding of the consequences of parental aging on child health and provide evidence of improving gamete quality prior to pregnancy as a preventative therapy.