Breath Testing for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis – Can Volatile Organic Compounds Predict Disease State and Treatment Response
Dr Thomas Goddard
Women’s and Children’s Health Network
CF is the most common fatal genetic condition in our community. Children die from respiratory disease caused by recurrent & chronic lung infections. Currently, sputum or broncho-alveolar lavage samples are cultured for several days before lung infection is diagnosed & treated. Because children cannot produce sputum on demand they can require an anaesthetic with a small camera inserted into their lungs to obtain the sample. However, if infections are detectable in the breath, diagnosis and monitoring is far simpler, cheaper and faster, enabling prompt treatment and prevention of disease.