Immune Monitoring in Renal Transplantation
Dr Paul Henning
Women’s and Children’s Hospital
Renal transplantation is the optimum treatment for children with kidney failure. Unfortunately transplant requires lifelong immune system suppression, and hence, the risk of life-threatening infections and cancer. Reducing immunosuppression to avoid these outcomes may result in kidney rejection and transplant loss. This research will explore a number of innovative immune system markers permitting fine-tuning of immune suppression treatment, such that the fine balance between over- and under-immunosuppression can be achieved, and survival of children with renal failure can be maximised.