Circular RNAs indicate placental ageing, signalling stillbirth risk and infant morbidity in survivors.
Chief Investigator: Dr Anya Arthurs [Early Career Researcher]
Funding Amount : $39,999
Recipient: Flinders University
Overview: Growth restricted babies are more likely to suffer stillbirth or neonatal death. Molecules called circular RNAs (circRNAs) accumulate in the stillbirth placenta and indicate premature placental ageing. We will determine if circRNAs in maternal blood indicate stillbirth risk and the therapeutic potential of mitigating DNA damage caused by accumulated circRNAs.