Treating early pregnancy T regulatory cell deficiency with IL-2/JES6-1 to boost maternal immune tolerance and reduce risk for inflammation-induced preterm labour.
Chief Investigator: Dr Kerrie Foyle [Early Career Researcher] Funding Amount: $39,538 Recipient: The University of Adelaide Overview: Preterm birth is the leading cause of childhood death, affecting nearly 1 in 10
Investigating proof-of-concept for genetic therapy of PCDH19-Clustering Epilepsy using preclinical mouse models.
Chief Investigator: Prof Paul Thomas Funding Amount: $99,988 Recipient: The University of Adelaide Overview: This project investigates the potential rescue of PCDH19-Clustering Epilepsy neuropathology through annulment of Pcdh19 in the brain.
Using gene editing and single cell RNA-seq to investigate FOSL transcription factors involvement in the breakdown in Treg-mediated immunological tolerance in type 1 diabetes.
Chief Investigator: Dr Timothy Sadlon Funding Amount: $100,000 Recipient: The University of Adelaide Overview: Type 1 diabetes (T1D) is a common and serious autoimmune disease in children caused by immune cell
Responding to the needs of kinship carers in South Australia.
Chief Investigator: Dr Fatin Shabbar [Early Career Researcher] Funding Amount: $40,000 Recipient: University of South Australia Overview: This study explores success factors and characteristics of kinship care that promote safety, stability
A novel prophylactic for the prevention of ventilator induced lung injury in preterm infants.
Chief Investigator: Dr Jack Darby Funding Amount: $99,987 Recipient: University of South Australia Overview: To survive being born too soon, preterm babies sometimes require ventilation or supplemental oxygen to help them
A new personalised immunotherapy for the deadly paediatric cancer neuroblastoma.
Chief Investigator: Dr Veronika Bandara Funding Amount : $100,000 Recipient: The University of Adelaide Overview: Neuroblastoma is a deadly paediatric cancer. We will test a new personalised immunotherapy, made by modifying the
Using Single Cell Sequencing to Elucidate the Clonal Evolution of Acute Lymphoblastic Leukaemia to Prevent Relapse in Children and Improve Outcomes.
Chief Investigator: Dr Susan Heatley Funding Amount : $99,838 Recipient: SAHMRI Overview: Acute lymphoblastic leukaemia is a devastating disease and we have reached the limit of what chemotherapy alone can achieve. It
From tank to treatment: Using zebrafish to find therapies for Sanfilippo syndrome childhood dementia and juvenile-onset Parkinson’s disease.
Chief Investigator: Dr Karissa Barthelson Funding Amount : $73,682 Recipient: Flinders University Overview: Our unique research strategy compares gene expression and behaviour patterns using machine learning in zebrafish models of two childhood