Treating early pregnancy T regulatory cell deficiency with IL-2/JES6-1 to boost maternal immune tolerance and reduce risk for inflammation-induced preterm labour.
Chief Investigator: Dr Kerrie Foyle [Early Career Researcher]
Funding Amount: $39,538
Recipient: The University of Adelaide
Overview: Preterm birth is the leading cause of childhood death, affecting nearly 1 in 10 babies. This project will test whether an agent that boosts anti-inflammatory immune cells prevents preterm birth in a mouse model. The results will inform development of interventions to improve outcomes for babies born premature.