From tank to treatment: Using zebrafish to find therapies for Sanfilippo syndrome childhood dementia and juvenile-onset Parkinson’s disease.
Chief Investigator: Dr Karissa Barthelson
Funding Amount : $73,682
Recipient: Flinders University
Overview: Our unique research strategy compares gene expression and behaviour patterns using machine learning in zebrafish models of two childhood dementias: Sanfilippo syndrome and juvenile-onset Parkinson’s disease. We will evaluate the therapeutic potential of drugs targeting cell functions dysregulated in both diseases, addressing an unmet need for these devastating diseases.